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Saturday, April 30, 2005

诺贝尔奖金得主的“尴尬” (A shameful story of a Nobel Prize Laureate)

       1975年,当年仅37岁的戴维 . 巴尔的摩登上诺贝尔领奖台时,他大概不会想到,拥有这样的殊荣,他的后半生的事业还会有波折。1986年他和他的一名助手Thereza Imanishi-Kari在Cell上发表了一篇免疫学方面的文章。Margot O'Toole当时是他们的一个博士后,受Thereza Imanishi-Kari的指导。Thereza Imanishi-Kari 把她的实验记录给Margot O'Toole,但是Margot O'Toole发现她并不能重复其中一些实验结果。她把这件事通了出来,这件事越闹越大,NIH和国会专门成立机构进行调查,巴尔的摩最后不得不撤回那篇论文。Margot O'Toole在事件发生后多年早不到工作,不得不到他弟弟的公司打工。Thereza Imanishi-Karibe被罚以不得从事联邦政府资助的研究多年,巴尔的摩的名誉在1992年后才开始挽回… …。

Thursday, April 28, 2005

Re: comment on acupuncture

Original comments on acupuncture:


Do you know acupuncture originated from China?

Mainstream American don't believe
Traditional Chinese medicine. So do I, even though I am a Chinese. However, we can not ignore Traditional Chinese medicine, such as acupuncture.

I just returned from ARO annual meeting from New Orleans. I was impressed a lot of works addressing tinnitus, which was addressed about two thousand years ago in ancient Chinese medical books, such as Huangdi Neijin literally or Chinese traditional medical "bible".

The illustration in the ancient books is much helpful to my research tinnitus----to find the tinnitus pathway. I just discovered a neuronal pathway associated with somatosensory tinnitus.

Tuesday, April 26, 2005

Fw: single cell retrieval for PCR

Wednesday, Carl Zeiss will demonstrate its Palm laser microdissection system for single cell retrieval for PCR. A laser beam isolates single cells from cell monolayers or tissue sections depositing them in individual Eppendorf tubes for molecular analysis. The operator examines the tissue section by light or fluorescence microscopy and circles the cells of interest on the computer monitor; a laser beam then cuts around each cell and pops it off and into a tube.

Demonstrations are Tuesday 4/26 through Thursday 4/28 in room 326 PCTB. A seminar on the technique will be presented in the Mountcastle Auditorium across from the cafeteria in PCTB at 1pm on Wednesday. Refreshments will be provided. Registration and scheduling with Zeiss are required. Contact : Jack Garner at jgarner@zeiss.com or call 800-543-1033 x7611.

Monday, April 25, 2005

Fw: JARO Editor Nominations

Dear ARO Member,

Dr. Eric Young, founding editor of the Journal of the Association for Research in Otolaryngology (JARO) has indicated a desire to step down as soon after the February 2006 ARO meeting as reasonable. With regret, and with the greatest thanks to Eric for doing a superlative job as editor for over 6 years, ARO accepts the fact that we must find a new editor.

According to ARO policy, all active members of ARO are invited to submit names for consideration for editor. The “job description” for editor in the JARO Policy guide states:

“The JARO Editor must be a member of ARO and be a highly regarded scholar who has an appreciation of the breadth of scholarship in our field. The JARO Editor also should have editorial, fiscal, and leadership experience, and have the highest professional and personal integrity. The JARO Editor serves a five-year renewable term.”

In addition, and based on the experiences of Dr. Young, it is clear that the JARO editor must have strong management skills, show a high level of organization, and have a strong commitment to the enhancement of JARO. Moreover, the new editor must be able to assemble a large group of Associate Editors and work with them, and with our publisher, to assure the highest quality papers and the highest quality journal.

We invite all ARO members to submit names of potential editors, and/or to nominate themselves. For each nomination please give the full name of the candidate and provide us with a 2-4 sentence reason for suggesting this person. Nominations without such a statement will not be accepted. Nominations should be sent via email to the co-chairs of the JARO Publications Committee, Gerald Popelka and Arthur Popper (popelka@ohns.stanford.edu, apopper@umd.edu). All nominations should be received no later than July 1, 2005.

Gerald R. Popelka, PhD, Co-Chair
Arthur N. Popper, PhD, Co-Chair
Publication Committee

Wednesday, April 20, 2005

Fw: Welch News: NIH Public Access Plan To Take Effect May 2, 2005

Beginning May 2, 2005, NIH funded researchers will be asked to submit voluntarily to the NIH National Library of Medicine's (NLM) PubMed Central (PMC) an electronic version of the author's final manuscript upon acceptance for publication, resulting from research supported, in whole or in part, with direct costs from NIH. After several months of heated debate, the policy was made public on February 3, making federally-financed research open and freely available to taxpayers and scholars alike. Scientific publishers opposed the plan, but other groups have hailed it as an historic moment in giving the public free access to information.

The author’s final manuscript is defined as the peer-reviewed, final version accepted for publication. Depositing one’s work is not mandatory, but scientists are widely expected to comply. NIH director, Elias A. Zerhouni, asks that scientists release their findings as quickly as possible, not delaying for the full 12 months. Aside from making research rapidly available to the public, the policy will create a stable, searchable archive of peer-reviewed research resulting from NIH funding.

Authors’ final manuscripts may be submitted in the usual electronic formats accepted by journals, e.g., most word processing formats or PDF. Once the manuscript has been submitted, the system will assign a PMC identification number and generate an e-mail to the author(s) confirming their submission. In cases in which the Principal Investigator (PI) is not an author, a courtesy e-mail will be sent to alert the PI of the submission. Corrections of content errors and other necessary revisions of authors’ final manuscripts will be accommodated.

At the time of voluntary submission to PMC, the author will specify when their final manuscript will be publicly accessible through PMC. Posting for public accessibility through PMC is strongly encouraged as soon as possible (and within twelve months of the publisher’s official date of final publication).

As additional details and instructions on the use of the PMC manuscript submission system become available, these will be posted on the NLM PMC website at http://www.pubmedcentral.nih.gov/. More information about the NIH Public Access Policy can be found at http://www.nih.gov/about/publicaccess/index.htm.

The journal, Neurobiology of Lipids (NoL), has already gone on record welcoming the NIH plan and announcing that they have met quality requirements for PubMed Central archiving. They urge authors to think of them when selecting a place to publish. They are developing a software tool that will simplify direct publishing to an archive. When scientists publish in NoL, their work will also automatically be archived in PubMed Central. NoL invites other funding agencies to follow NIH’s lead and other journals to consider depositing full text in PubMed Central.

In a recent letter to the Public Library of Science Community (PLoS), the three founders of PLoS, Drs. Harold Varmus, Patrick Brown and Michael Eisen, urged authors to (a) publish papers in open-access journals that already deposit their papers to PubMed Central or (b) if authors publish in non open access journals, deposit those manuscripts into PubMed Central and exercise the right to stipulate that they be posted online immediately after publication.

Brian Brown, MLIS
Communications Librarian
Welch Medical Library
The Johns Hopkins University

410.502.7568 (Welch)
410.502.0995 (BRB)

Fw: Hopkins Biotech Network -- Baltimore Social Hour at Ruby Tuesday\'s

Please join us for our first HBN Baltimore Social Hour!

The purpose of the event is to meet and network with other HBN members in the Baltimore area.

Please come and share your ideas for upcoming HBN events and activities.

Ruby Tuesday\'s is located on Charles Street, next to the Homewood Campus, and within a five minute walk from the Homewood/JHMI shuttle stop.


Date/Time: Wednesday, April 27th, 5:30pm
Location: Ruby Tuesday\'s
3003 N Charles St
Baltimore, MD. 21218
Phone: (410) 467-8155


Hopkins Biotech Network (HBN)

HBN Partners
Baxter (http://www.baxter.com/)
Greater Baltimore Committee (http://www.gbc.org/)
Guilford Pharmaceuticals (http://www.guilfordpharm.com/)
Hopkins Capital Group (http://www.hopkinscap.com/)
Nutrition 21 (http://www.nutrition21.com/)